KMID : 0861420120160020120
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Korean Journal of Nuclear Medicine Technology 2012 Volume.16 No. 2 p.120 ~ p.125
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Comparison of Attenuation Correction Methods for Brain SPECT Ima
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Cho Jin-Woo
Kim Chang-Ho Na Soo-Kyung Lee Gui-Won
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Abstract
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Purpose:The purpose of this study was to compare count between Chang¡¯s method and CT-based attenuation
correction (AC-CT) among the attenuation correction (AC) methods for non-attenuation correction (AC-non)
images of Brain SPECT (Single Photon Emission Computed Tomography).
Materials and Methods: We injected 99mTc 37Mbq in a Hoffman 3D phantom filled with distilled water in the phantom study, and injected intravenously 99mTc-HMPAO 740Mbq in a normal volunteer in the patient study, and then obtained Brain SPECT images with Symbia T6 of Siemens and conducted quantitative brain analysis. Transverse images to which each method was applied were rebuilt at the same position, and 6 regions of interest (ROI) were drawn on
each of Slice No. 10, 20 and 30 and then the counts of AC-non, AC-CT and Chang¡¯s method were compared.
Results:The mean counts of AC-non, AC-CT and Chang¡¯s method were 4606.8 ¡¾ 511.3, 16794.6 ¡¾ 2429.4, and
8752.6 ¡¾ 896.5, respectively, in the phantom study and 5460.8 ¡¾519.6, 15320 ¡¾ 1171.6 and 12795 ¡¾ 1422.1,
respectively, in the patient study. In the phantom study, the ratio of AC-CT to AC-non was 3.70 and the ratio of
Chang¡¯s method to AC-non was 1.92, and in the patient study, they were 2.85 and 2.38, respectively.
Conclusion: From this study, we found that AC-CT makes higher AC than Chang¡¯s method. In addition, when Chang¡¯smethod was used, AC in the patient study was higher than that in the phantom study. These results need to be
considered also in other examinations.
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KEYWORD
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Brain SPECT, Attenuation correction(AC), Chang¡¯s method
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